Publication

Alcohol Exposure

+ = reported

Gestational Age/Birth Weight

Growth Impairment

Facial Features

Neurocognitive Impairments

FASD Status

[34]

+

Term 1600 g

WT, HC <10% at birth

SPL, FP, TUL, micrognathia and low set ears

Brain was histologically normal on autopsy

FAS

[35]

+

35 weeks 1360 g

HC, HT, WT <3% at birth

Hypertelorism, broad nasal bridge, inferolateral deviation of right eye, low-set and posteriorly rotated right ear,

Microcephaly and partial agenesis of the corpus callosum

FAS

[36]

+

Reported

Described as abnormal

FAS

[36]

+

Reported

Described as abnormal

FAS

[37]

+

37 weeks 2330 g

WT, HT, HC, CC <3rd %

Long upper lip, cleft palate, hypertelorism, partial ptosis, curved fused eyebrows1

Absence of corpus callosum and underdevelopment of cerebellar vermis, areas of necrosis in the brain2

FAS

[37]

+

32 weeks 1180 g

WT, HT, HC, and CC <3rd %

Reportedly similar to previous case

Brain was small for developmental age (395 grams at 4 months)3

FAS

[37]

+

Term Not reported

Similar to previous cases without cleft palate

Abnormalities of cortical mantle formation4

FAS

[37]

+

35 weeks 1525 g

WT (1525 g), HC (28.5) both small for gestational age

Nondiagnostic facial features (flat nasal bridge and recessive mandible)

Brain was heavy (405g) but small5

FAS

[37]

+

29 weeks 880 g

WT below 3rd %

Reported facial features to be similar to the other cases in the paper

Brain small for gestational age (124.5 g) and an area of heterotopia white matter of the temporal lobe

FAS

[38]

+

Term 1770 g

Reduced birth weight, growth deficiency at 2 years

Blepharophimosis, SPL, flat nasal bridge, bilateral ptosis, and EF

Microdysplasias (partial fusion of third ventricle), spongiform loosening in the optic nerve and in the hypothalamus, seizures, psychomotor retardation

FAS

[38]

+

Term

Blepharophimosis, hypertelorism, micrognathia, hypoplastic ears, short upturned nose, and cleft palate

Hydrocephalus internus, heterotopic gyri in cerebellar white matter, slowed maturation of cerebral and cerebellar white matter

FAS

[38]

+

SPL, TUL, and low set ears

Seizures, porencephaly, hydrocephaly, agenesis of corpus callosum, multiple other abnormalities

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

FAS

[26]

+

Status epilepticus at 18 months, hemiplegia

FAS

[26]

+

FAS

[26]

+

FAS