Publication |
Alcohol Exposure + = reported |
Gestational Age/Birth Weight |
Growth Impairment |
Facial Features |
Neurocognitive Impairments |
FASD Status |
[34] |
+ |
Term 1600 g |
WT, HC <10% at birth |
SPL, FP, TUL, micrognathia and low set ears |
Brain was histologically normal on autopsy |
FAS |
[35] |
+ |
35 weeks 1360 g |
HC, HT, WT <3% at birth |
Hypertelorism, broad nasal bridge, inferolateral deviation of right eye, low-set and posteriorly rotated right ear, |
Microcephaly and partial agenesis of the corpus callosum |
FAS |
[36] |
+ |
Reported |
Described as abnormal |
FAS |
||
[36] |
+ |
Reported |
Described as abnormal |
FAS |
||
[37] |
+ |
37 weeks 2330 g |
WT, HT, HC, CC <3rd % |
Long upper lip, cleft palate, hypertelorism, partial ptosis, curved fused eyebrows1 |
Absence of corpus callosum and underdevelopment of cerebellar vermis, areas of necrosis in the brain2 |
FAS |
[37] |
+ |
32 weeks 1180 g |
WT, HT, HC, and CC <3rd % |
Reportedly similar to previous case |
Brain was small for developmental age (395 grams at 4 months)3 |
FAS |
[37] |
+ |
Term Not reported |
Similar to previous cases without cleft palate |
Abnormalities of cortical mantle formation4 |
FAS |
|
[37] |
+ |
35 weeks 1525 g |
WT (1525 g), HC (28.5) both small for gestational age |
Nondiagnostic facial features (flat nasal bridge and recessive mandible) |
Brain was heavy (405g) but small5 |
FAS |
[37] |
+ |
29 weeks 880 g |
WT below 3rd % |
Reported facial features to be similar to the other cases in the paper |
Brain small for gestational age (124.5 g) and an area of heterotopia white matter of the temporal lobe |
FAS |
[38] |
+ |
Term 1770 g |
Reduced birth weight, growth deficiency at 2 years |
Blepharophimosis, SPL, flat nasal bridge, bilateral ptosis, and EF |
Microdysplasias (partial fusion of third ventricle), spongiform loosening in the optic nerve and in the hypothalamus, seizures, psychomotor retardation |
FAS |
[38] |
+ |
Term |
Blepharophimosis, hypertelorism, micrognathia, hypoplastic ears, short upturned nose, and cleft palate |
Hydrocephalus internus, heterotopic gyri in cerebellar white matter, slowed maturation of cerebral and cerebellar white matter |
FAS |
|
[38] |
+ |
SPL, TUL, and low set ears |
Seizures, porencephaly, hydrocephaly, agenesis of corpus callosum, multiple other abnormalities |
FAS |
||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |
||||
[26] |
+ |
Status epilepticus at 18 months, hemiplegia |
FAS |
|||
[26] |
+ |
FAS |
||||
[26] |
+ |
FAS |